Which the Analysis That Must Be Carried out During Pregnancy?

The health of the mother and the fetus should be monitored throughout pregnancy.

After confirmation of pregnancy, the doctor may prescribe a series of reviews aimed at verifying the State of general health of pregnant and ensure a safe pregnancy.

From a medical point of view, the period of pregnancy is divided into 3 quarters, in which analyses are performed. The more specific aim to assess immunization for toxoplasmosis, rubella, Cytomegalovirus or possible infections arising during the pregnancy, in order to safeguard the well-being of the mother and the fetus. It is also carried out research on hepatitis B, syphilis and AIDS virus (HIV).

The evaluation of the levels of blood sugar and screening of gestational diabetes are also a very important parameter, since elevated levels can trigger problems in the development and growth of the fetus.

Urine analyses are also taken into consideration during pregnancy and is an excellent indicator of proper functioning. Urine culture sense also the possible urinary infections, which in pregnant are often asymptomatic.

The Cbc is also an important and mandatory pregnancy analysis, requested between 1st and 8th week of gestation, and analyzes the blood moving in the body of pregnant to determine the amount of red blood cells and the iron reserve, losing so many types of anemias, such as ferropenicas, caused by iron deficiency.

During pregnancy it is still central to the determination of blood group and Rh factor, in order to check the blood incompatibility between the mother and the fetus, since the incompatibility causes destruction of red blood cells in the fetus, which affects your survival. The Rh factor becomes important if the mother is Rh negative and the fetus is RH-positive, which can occur if the father is Rh positive and the baby inherit this feature. In these situations, if the blood from the fetus enter the bloodstream of the mother, the immune system can react against the D Antigen of the baby’s blood and produce antibodies against it.

Analytical routines per quarter

 

1st quarter

  • ABO typing and Rh factor
  • Irregular agglutinins research (indirect Coombs test)
  • Complete Blood Count
  • Fasting blood sugar
  • VDRL-syphilis Screening
  • Rubella serology-IgG and IgM
  • Screening of HIV Infection
  • Hepatitis B screening
  • Screening of asymptomatic bacteriuria
  • Biochemical screening of the 1st quarter, the PAPP-A (pregnancy associated Plasma Protein) and ß-HCG (Subunit Chorionic Gonadotrófica hormone free), with great sensitivity and specificity for the screening of Trisomies 21, 18 and 13.

 

2nd Quarter

 

Between the 18th – 20th Week

  • Rubella Serology

Between 24th-28th Week

  • Complete Blood Count
  • PTGO c/75 g
  • Toxo-IgG and IgM serology
  • Urine culture with possible antibiotic sensitivity test
  • Irregular agglutinins research (indirect Coombs test) in Rh negative women *
  • Biochemical screening of the second quarter, the PAPP-A and the AFP (alpha-fetoprotein)

* In the 4 weeks before the administration of anti-D immunoglobulin

 

3rd Quarter

 

Between 32nd-34th Week

  • Complete Blood Count
  • VDRL
  • Toxo-IgG and IgM serology (in women not immune)
  • HIV 1 and 2.
  • Hepatitis B screening, Hbsag, (only non-vaccinated pregnant women and not immune in the 1st quarter).
  • Urine culture with possible antibiotic sensitivity test (SRT)

Between the 35th-37th Week

  • Harvest (1/3 of the vagina and anorectal) for specific search of Streptococcus? hemolytic Streptococcus Group B

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