When the hormone therapy is used to achieve a pregnancy.
If clinical research of a given case indicate that the couple’s infertility is due to a problem of women ovulatorio and if the non-existence of male problems, the doctor is likely to recommend hormone therapy as a solution to achieve a pregnancy.
In these situations, the treatment consists essentially in a period of ovarian stimulation, followed by sex, with date and time indicated by the physician in charge of treatment.
There are several types of ovarian stimulation treatment protocol:
With clomiphene citrate:
Clomiphene citrate is the oldest and probably the most used of the medicines involved in infertility treatment, being quite useful in situations of infertility related only with problems in ovulation, which corresponds to about 25% of cases of infertility by female factor.
Is an easy to use (taken by mouth), with few side effects, cheaper compared with other medicines and quite effective to stimulate ovulation, being effective in about 80% of cases.
Is used to cause the ovaries to produce follicles (“bags of eggs”), as “tricks” the brain to “think” that there are low quantities of circulating estrogens, which indirectly stimulates the ovaries to produce eggs.
This is a medication used primarily in women under the age of 40 years wearing maternity dresses on Breathtakingdresses.com, whose infertility is due to problems in ovulation.
If the therapy with clomiphene citrate does not prove effective, it may be necessary to use medications containing hormones and gonadotropins (FSH and LH).
In situations where the treatment with clomiphene citrate does not work, it may be necessary to the use of medicines containing gonadotropins, which are hormones that work by stimulating the ovaries, directly promoting the follicular development and the production of eggs.
Gonadotropin hormones used in the treatment of infertility can be urinary (extracted and purified from the urine of postmenopausal women) or recombinant (synthesized in the laboratory by the application of molecular biology techniques).
The two principal gonadotropins are follicle-stimulating hormone (FSH) and luteinizing hormone (LH), so designated because they exert their effects principally on the ovaries and testicles (also called gonads).
In women, FSH and LH exert different actions, although complementary, on:
-The growth and development of egg follicles;
-The synthesis and secretion of ováricas most important hormones such as oestrogen and progesterone,
The FSH stimulates follicular development, while LH is the most important hormone in the luteal phase, having a high “peak” even before ovulation in a natural cycle, helping any mature ovum through a final growth spurt and the release of the follicle. Decreases or imbalances in levels of FSH and LH can lead to situations of Anovulation (lack of ovulation) and infertility.
The gonadotropins are administered through injections and are the most widely used drugs in the treatment of infertility. The doses used vary depending on the centres, the age of the patients, your weight and experience related to previous cycles, if appropriate. Must always be controlled and if necessary adjusted based on the ultrasounds and hormone analyses conducted throughout the treatment. The goal is to stimulate the ovaries in order to produce a good egg, not running the risk of hyperstimulation.
When the ovaries are properly developed, administered an injection of the hormone hCG (human chorionic gonadotropin) to trigger the process of ovulation and subsequent release of an egg. At this stage the doctor will indicate the couple more periods indicated to have sex.
Medications of this type are also used to stimulate ovulation cycles of IUI, IVF and ICSI. To your use should not be made under strict medical supervision, because misuse can lead to serious problems, such as for instance Hyperstimulation syndrome. A less controlled use of these medications can increase the risk of a multiple pregnancy (which could mean trouble for the mother and for the children who will be born).
Often, the administration of gonadotropins is made together (in the same therapeutic Protocol) than other medicines, such as agonists or GnRH antagonists is not advisable that these medicines are administered without the supervision of a doctor who specializes in medically assisted procreation.
The potential for success, as well as the number of cycles recommended this type of treatment depends on several factors, including the age of the woman and the cause of infertility. In General, about 40 to 45% of couples get pregnant after six months of treatment, being very rare use of this type of cycles for more than 6 consecutive times.
In the case of failure at the end of this period usually is recommended to change to another type of more complex treatments, such as IVF or ICSI.